Processing and validation of natural materials for TERM

Processing and validation of natural materials for TERM

Objective: To select and process natural biomaterials that could be used for tissue regeneration, by using different processing and/or surface modification methodologies.

Natural based multi-functional scaffold for therapeutic applications: Design and Fabrication

Natural based multi-functional scaffold for therapeutic applications: Design and Fabrication

Objective: Fabrication of TERM bioactive scaffold with tailored biological and physical properties made with selected natural materials.

Definition and optimization of in vitro protocols and testing

Definition and optimization of in vitro protocols and testing

Objective:

  • Definition of commons protocols for the in vitro biological assessment of the scaffolds;
  • Design and fabrication of bioreactors for long-term cell cultures in static and dynamic conditions, also to induce prevascularization;
  • Validation of cell-seeded scaffolds as models substitutive to animal testing.
Natural materials for stem cell tissue engineering therapy

Natural materials for stem cell tissue engineering therapy

Objective: to investigate the effect of the different selected materials on stem cells differentiation, by using different progenitor cells and considering tailored possible applications (e.g., cartilage, bone..).

ESR Training

ESR Training

Objective: training of 24 early stage researchers

Management (Management, Networking)

Management (Management, Networking)

Objective: coordination and management of the project, update of the workplans, reporting, harmonization of the activities.

Dissemination, Communication and exploitation

Dissemination, Communication and exploitation

Objective: diffusion to the scientific community of the scientific results and to the public. Technology transfer, translation to the clinics.

Ethics requirements

Ethics requirements

Objective: to ensure compliance with the 'ethics requirements' set out in this work package.